Genetic mutation is a change in the sequence of DNA that occurs during cell division, radiation exposure, exposure to mutagens, or viral infection. Germline mutations occur in the reproductive cells like the sperm or egg, thereby passing onto the offspring. In contrast, somatic mutation takes place in the body's cells and so does not pass on. Cystic fibrosis, sickle cell anemia, etc., are few examples of inherited genetic disorders which involve single gene mutation.
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Can BF1 gene mutation be the reason for my obesity?
Query: Hello doctor, I am a 34-year-old male and weigh 280 pounds. I have tried everything I could come across or thought would help to lose weight. However, nothing worked. I read of a BF1 genetic mutation that can result in persistent obesity. Is this true? How can I know if this is the reason behind my ... Read Full »
Answer: Hello, Welcome to icliniq.com. Your first query consult is on us! Your concern is valid. Obesity occurs due to high carbohydrate intake with less physical activity. It can be due to drastic hormonal changes as well, which are related to your current age, as you are 34 years old. We need to find o... Read Full »
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