I have two specific questions. I am trying to conceive, and I am trying to be as careful as possible about taking any medications that could harm the fetus should I get pregnant. My questions have to do with the two medications. I am currently prescribed Desonide cream 0.05 percent (pregnancy category C) for moderate psoriasis on my face and three to four patches on my limbs, with a large one on the front of my knee. I have been using it a couple of times a week for almost two years (I am still on the same tube), so I am using it sparingly. Although my dermatologist told me that I am safe to use while trying to conceive and even during my first trimester, I wanted to get an opinion from a toxicologist. I intend to discontinue the use of all medications the minute I find out I am pregnant. However, I am questioning the safety of its use during the period I am trying to conceive. I have the same question for a medication I have been prescribed for the past several years for my diagnosed attention deficit hyperactivity disorder (ADHD) Dextroamphetamine 5 mg twice a day (I am a busy attorney who needs this small dose of medication to function at the level I need to). My prescribing doctor advises me that I can safely take this medication while trying to conceive but would not recommend it while pregnant. Here is my dilemma. I plan on discontinuing all medications the minute I find out I am pregnant. I take an at-home pregnancy test each month before and after my scheduled menstruation, so I hope even if I got pregnant, it would be before the placenta formed and would not harm the fetus. However, since I have been on these prescribed medications, albeit at low doses, for some length of time, do I need to be concerned about any build-up in my system harming the fetus even if I quit as soon as I know I am pregnant at about three to four weeks? Can I safely continue to take my medications during the "trying to conceive" period? My doctors sound kind of unsure at the same time; they are telling me it is fine. Please help. I am so concerned about our unborn child's safety that I can barely sleep at night.