Mao Inhibitor

Monoamine oxidase inhibitors (MAO) inhibitors are a group of antidepressants that treat depression. They help ease depression by changing levels of brain chemicals (serotonin, dopamine, and norepinephrine) called neurotransmitters. They inhibit an enzyme called monoamine oxidase, which breaks down norepinephrine, serotonin, and dopamine, allowing neurotransmitters to remain in the brain, thus improving mood through improved brain cell communication. Common side effects of MAO inhibitors include headache, dry mouth, dizziness, blurred vision, high blood pressure, muscle cramps, low sex drive, weight gain, blurred vision, nausea, diarrhea, and skin irritations. While taking MAO inhibitors, diet restrictions and avoiding other antidepressants are necessary as they can cause high blood pressure and other medical problems.

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Is it acceptable to take Levothyroxine with an MAO inhibitor?

Query: Hello doctor, I am wondering if I can take Levothyroxine along with MAO inhibitor? Also, I have taken Etizolam for a sleep disorder, how long do I need to wait before I can take MAO inhibitor?  Read Full »


Dr. Amrit Agarwal

Answer: Hello, Welcome to icliniq.com. You can take Levothyroxine with MAO (monoamine oxidase) inhibitor. The list of contraindicated drugs is as follows. Amphetamines. Cocaine. MDMA (3,4-Methylenedioxymethamphetamine). Opiates. Barbiturates. Decongestants and allergy medications. Diet pills...  Read Full »

Do I have to stop taking MAO inhibitor before my L3, and L4 spinal surgery?

Query: Hello doctor, I am 79 years old. I am having spinal surgery on L4 and L3 next month. I have been on 90 mg of Nardil,an MAOI, for the last 32 years. Is there any general anesthesia that can be used so that I do not have to come off this medication, or do I have to be off it two weeks before surgery?  Read Full »


Dr. Arul

Answer: Hello, Welcome to icliniq.com. The anesthetic drugs and their dose are carefully chosen after considering patients age, general health, condition of vital organs, previous history of diseases, concomitant medications, and duration of surgical procedure, etc. Hence, before any elective surgery, the...  Read Full »

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