How does olive oil help in reducing inflammation?

Question

Hi doctor,

I recently read an article about the health benefits of olive oil, particularly in relation to reducing inflammation and possibly preventing dementia. As someone with a family history of cognitive decline, I am very interested in this. Can you explain how olive oil might help with inflammation and brain health? I am wondering how much olive oil I should consume daily to potentially see benefits and if extra virgin olive oil is better than other types. Also, are there any specific ways I should incorporate it into my diet? I am curious about whether olive oil alone can make a significant difference or if it is part of a broader Mediterranean diet that is beneficial. Lastly, is there any solid scientific evidence supporting these claims about olive oil's effects on inflammation and dementia risk? Please advise.

Thank you.

Answer 1

Hi,

Welcome to icliniq.com.

I read your query and understand your concern.

A study conducted on mild cognitive impairment patients has shown that intake of extra-virgin olive oil for over 12 months is associated with increased levels of neuroprotective (the ability of a therapy to prevent neuronal cell death) proteins in serum, which in turn is associated with a reduction in oxidative stress (an imbalance of free radicals and antioxidants in the body, leading to cell damage) and inflammation.

Mechanistical evidence from animal and human studies has shown that phenolic compounds in olive oil, particularly extra-virgin olive oil, may attenuate inflammation, and oxidative stress and restore the blood-brain barrier (a selective semi-permeable membrane between the blood and the interstitium of the brain) function, thereby reducing brain amyloid-β and tau-related pathologies and improving cognitive functions. Olive oil's main anti-inflammatory effects are from antioxidants, one of which is oleocanthal. This antioxidant has been shown to work like Ibuprofen, an anti-inflammatory drug.

There is some evidence that certain nutrients can help reduce brain inflammation. These include omega-3 fatty acids, curcumin (a component of turmeric), and green tea. Adding these nutrients to your diet, especially sufficient essential fatty acids, may help reduce symptoms. Most people commonly use olive oil as medicine for heart disease, diabetes, and high blood pressure. It is also used for high cholesterol, cancer, memory and thinking skills, migraine, obesity, and many other conditions, but there is no good scientific evidence to support many of these other uses

I hope that you get your answer.

Please let me know if you need any help.

Thank you.