HomeAnswersHematologyenlarged spleenShould I do blood works regularly to monitor my enlarged spleen?

Should an enlarged spleen be a matter of concern?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

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iCliniq medical review team

Published At June 23, 2023
Reviewed AtFebruary 6, 2024

Patient's Query

Hello doctor,

I am a 32-years- old male, 5.61 feet, and 178 lbs. I have had an enlarged spleen of 5.51 inches to 5.91 inches since many years. No other symptoms and every six months I get my blood work done with normal results. Should I pursue this more? My pathologist says it could be my normal size spleen.

Hi,

Welcome to icliniq.com.

I read your query and understand your concern. Enlarged spleen is seen in liver diseases, hemolytic anemia, parasitic infestation especially malaria, autoimmune disorders, rheumatological diseases. An enlarged spleen is not normal at all, this can cause symptoms, sooner or later. A 5.51 inches to 5.91 inches spleen is considerably enlarged. I have never seen a normal spleen of this size in my life. I suggest to get a hemoglobin electrophoresis, ESR (erythrocyte sedimentation rate), CRP (c-reactive protein), LDH (lactate dehydrogenase), ALT (alanine transaminase), creatinine levels for further evaluation.

Patient's Query

Hello doctor,

Thank you for your response. I did the recommended tests, my GP says they are normal. All of the below are withing normal ranges:

1. ESR: 2 mm/h

2. LDH: 316 units/L

3. ALT: 12.6 U/L

4. AST: 17.9 U/L

5. Creatinine: 0.97 mg/dL

6. Total bilirubiin levels: 1.2 mg/dL

Hello,

Welcome back to icliniq.com.

Good to know that you have already got tested and results are in range. However, bilirubin total is at upper limit, so keep monitoring bilirubin on monthly basis. Get a course of anthelmintic and anti-malaria on empirical or prophylactic basis. I hope I have cleared all your doubts.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Mubashir Razzaq Khan
Dr. Mubashir Razzaq Khan

Hematology

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