Is it safe to pair Gabapentin with Metoclopramide?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I suffer from chronic migraines, and I take Gabapentin, 1800 mg daily for prevention. Recently, a general practitioner (GP) recommended Metoclopramide, 30 mg daily to help with nausea, but I have yet to take it, as I am concerned about the combination. Is this a safe pair of drugs to use together? Thank you.

Hi,

Welcome to icliniq.com. I read your query and understand your concerns. I would like to state that Gabapentin and Metoclopramide have no major interactions and can be taken together. However, there are reports of increased side effects such as giddiness and sedation. Some of the individuals with this combination report difficulty in concentrating and driving. Considering the above facts, I like to advise you to avoid operating any kind of heavy machinery, for example, driving, during the initial three to four days till you are comfortable. Your general practitioner (GP) is right and if the nausea is still problematic, you can opt for Metoclopramide. I hope this answers you. If you have more questions feel free to write back to me. Thanks and regards.

Medically reviewed byDr. K. Shobana

Published At October 1, 2017
Reviewed AtJuly 16, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Listen to related tracks in our music library

Read answers about:

drug interactionsmigraine

Ask your health query to a Wellness Expert online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy