Is it safe to pair Gabapentin with Metoclopramide?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I suffer from chronic migraines, and I take Gabapentin, 1800 mg daily for prevention. Recently, a general practitioner (GP) recommended Metoclopramide, 30 mg daily to help with nausea, but I have yet to take it, as I am concerned about the combination. Is this a safe pair of drugs to use together? Thank you.

Answered by Dr. Ashok Kumar Choudhary

Education:

MBBS

Professional Bio:

Dr. Ashok Kumar Choudhary is a skilled Psychiatrist specializing in andrology, geriatrics, sexology, and general psychiatric care. He focuses on diagnosing and managing mental health conditions, sexual health issues, and age-related psychological concerns. With a compassionate and patient-centered approach, Dr. Choudhary provides personalized care aimed at improving mental well-being, quality of life, and overall health.

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Hi,

Welcome to icliniq.com. I read your query and understand your concerns. I would like to state that Gabapentin and Metoclopramide have no major interactions and can be taken together. However, there are reports of increased side effects such as giddiness and sedation. Some of the individuals with this combination report difficulty in concentrating and driving. Considering the above facts, I like to advise you to avoid operating any kind of heavy machinery, for example, driving, during the initial three to four days till you are comfortable. Your general practitioner (GP) is right and if the nausea is still problematic, you can opt for Metoclopramide. I hope this answers you. If you have more questions feel free to write back to me. Thanks and regards.

Medically reviewed by Dr. K. Shobana
Published At October 1, 2017
Reviewed At July 16, 2025

Education:

MBBS

Professional Bio:

Dr. Ashok Kumar Choudhary is a skilled Psychiatrist specializing in andrology, geriatrics, sexology, and general psychiatric care. He focuses on diagnosing and managing mental health conditions, sexual health issues, and age-related psychological concerns. With a compassionate and patient-centered approach, Dr. Choudhary provides personalized care aimed at improving mental well-being, quality of life, and overall health.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ashok Kumar Choudhary
Dr. Ashok Kumar Choudhary

Geriatrics

Consult this doctor

Education:

MBBS

Professional Bio:

Dr. Ashok Kumar Choudhary is a skilled Psychiatrist specializing in andrology, geriatrics, sexology, and general psychiatric care. He focuses on diagnosing and managing mental health conditions, sexual health issues, and age-related psychological concerns. With a compassionate and patient-centered approach, Dr. Choudhary provides personalized care aimed at improving mental well-being, quality of life, and overall health.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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