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Arnuity Ellipta - the Best Fluticasone Furoate Inhalation Powder

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Arnuity Ellipta - the Best Fluticasone Furoate Inhalation Powder

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Arnuity Ellipta contains Fluticasone furoate in powdered form and used for prophylactic medicine in the treatment of asthma. This article discusses about effects of Arnuity Ellipta on the respiratory system, its dosage, side effects, complications and contraindications.

Medically reviewed by

iCliniq medical review team

Published At July 4, 2016
Reviewed AtFebruary 27, 2024

Asthma is characterized by bronchospasm, airway narrowing and inflammation of the respiratory tract. Some researchers believe that it is due to some allergens such as dust particles, fumes, chemicals, etc., that initiate the allergy and cause inflammation of the lung tissues.

Approval of Fluticasone Furoate Inhalation Powder

There are many varieties of inhalation powders available in the market. Arnuity Ellipta is one type of inhalation powder, which is beneficial in asthma. Recently, in London, the US Food and Drug Administration has given approval for its use as inhalation powder in asthma. This powder is used in asthma as maintenance therapy. The most effective and approved dose is 100 or 200 mcg of Arnuity Ellipta. This powder is inhaled through one specific inhaler, which is known as ellipta. GSK has researched for the efficacy of Arnuity Ellipta on 3600 asthmatic patients, aged above 12 years, and proved that it reduces the asthmatic attack.

Dosage

It should be taken once in a day. Large dose is not indicated and causes harmful effects. The gap between two doses is 24 hours minimum. The patient should start taking the powder with 100 mcg. The dose should be increased as per asthma severity, but should not exceed 200 mcg at a time. After two to three weeks of initiation, the patient may take 200 mcg of this powder, if 100 mcg does not produce any beneficial effects in asthma. Usually, it is the best to prevent recurrent asthmatic attack and aggravation. It decreases the inflammation of the tract and reduces the production of mucus. Mechanism of action is not yet properly understood.

Side Effects

There are a few side effects associated with its use.

  1. They are fungal or yeast infection in the mouth, infection of the nose and throat or pharynx, headache, inflammation of bronchus and alveolus, and hoarseness of voice. Mouth rinsing is essential to prevent the chances of yeast infection in the mouth.
  2. Adrenal gland suppression, hepatic impairment and hypercorticism may occur with very high dosage.

Complications

Some rare complications with the use of Fluticasone furoate inhalation powder are:

Contraindications

It is restricted in the following conditions.

  1. Acute attack of asthma.
  2. Management of status asthmaticus.
  3. Person with milk protein allergy.
  4. Allergy to any of its ingredients.

This inhaler does not provide relief in acute condition characterized by severe symptoms and acute bronchospasm. Withdrawal of this inhalation powder should be gradual with tapering dose. Sudden withdrawal is not recommended. Intake for prolonged duration also causes reduction in the density of bone.

If it is inhaled through the mouth into lungs, its 13% is delivered into lungs. However, if it is swallowed through the mouth, only 1.3% is available for its efficacy. Therefore, it is the best orally inhaled corticosteroid powder. The larger amount is eliminated from the body through feces and smaller amount through urine.

To know more about the treatment of asthma, consult an asthma specialist online --> https://www.icliniq.com/ask-a-doctor-online/pulmonologist/asthma

Frequently Asked Questions

1.

Is Arnuity Effective for Asthma?

Arnuity helps to control and prevent the symptoms of asthma. However, it does not work immediately and is not used to relieve sudden asthma attacks. It is advisable always to have a rescue inhaler to treat sudden asthma attacks.

2.

Does the Arnuity Inhaler Contains Steroids?

Fluticasone furoate is the generic name for Arnuity, and it belongs to a class of drugs called corticosteroids. It reduces swelling of the airways in the lungs and makes breathing easier. This drug must be used regularly to get good results

3.

When Is the Ideal Time to Take an Arnuity Ellipta?

Arnutiy should be taken once a day, and it is suggested to take it at the same time each day. However, the best time to take an asthma inhaler is in the evening.

4.

What Inhalers Are Similar to Arnuity?

Flovent Diskus and ArmonAir are similar to Arnuity; all these are powder forms of Fluticasone. They all come in a special inhaler device with blister packs containing the required quantity of Fluticasone.

5.

How Long Does the Arnuity Ellipta Stay In Our Body?

Most inhaled corticosteroids are more effective and stay in our system for about 12 hours. Whereas the Arnuity ellipta is expected to stay in our system for about 24 hours.

6.

What Is the Use of Fluticasone Furoate Inhalation Powder?

Fluticasone is in a class of medications called corticosteroids. It is used to prevent difficulty in breathing, wheezing, coughing, and chest tightness caused by asthma in adults and children.  It reduces swelling of the airways in the lungs and makes breathing easier.

7.

What Happens if Arnuity Ellipta Is Stopped Suddenly?

If the Arnuity ellipta is stopped suddenly, it can cause withdrawal symptoms such as weakness, nausea, muscle pain, dizziness, headache, tiredness, and weight loss. To help prevent these withdrawal symptoms, healthcare professionals may slowly lower the dose of the medication.

8.

Can Flonase and Arnuity Taken Together?

Studies say that when Flonase and Arnuity are taken together, no interactions are found. However, this does not mean no interactions exist. So it is important to consult a healthcare provider before taking any drug.

9.

Is the Usage of Arnuity Safe During Pregnancy?

The Asthma Management Handbook recommends Fluticasone, Ciclesonide, and Beclomethasone, with less evidence for safety during pregnancy. So consult your healthcare provider before using any drugs during pregnancy.

10.

In Which Category Does Fluticasone Belong?

Fluticasone belongs to a class of medications called corticosteroids. Corticosteroids are a copy of a substance that our body makes naturally. Fluticasone nasal spray is available on prescription for adults and children.

11.

Why Are Inhaled Steroids More Effective Than Oral?

Inhaled steroids are more effective because they are delivered directly to the lungs and require only smaller doses. It also has fewer side effects, so it can be used in the long term.

12.

Is There a Weight Gain Chance While Using a Fluticasone Inhaler?

Steroid nasal sprays like Fluticasone are not directly associated with weight gain as oral steroids because they are not system-wide drugs. However, they can still cause weight gain when used in high dosages.

13.

Is Fluticasone Helpful in Mitigating Inflammation?

Fluticasone effectively reduces the symptoms related to inflammatory conditions and allergic reactions such as redness, swelling, and itching. It also reduces inflammation of the airways in the lungs and makes breathing easier.

14.

When Is the Possible Generic Entry for Arnuity Ellipta?

Currently, there are no generic alternatives to Arnuity ellipta. The earliest date for generic availability of the Arnuity ellipta will be October 2, 2027.

15.

What Is the Dosage of Arnuity Ellipta?

Arnuity ellipta should be administered orally, with one inhalation once daily. This drug should be used at the same time daily. Using this drug more than once every 24 hours is not recommended.
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Talati Vidhi Hareshbhai
Talati Vidhi Hareshbhai

Physiotherapy

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