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Trends of Male Factor Infertility

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Infertility can affect all age groups and sexes and is a significant problem. It affects 50 percent of males globally. Read the article to learn more about it.

Medically reviewed by

Dr. Sameer Kumar

Published At April 4, 2023
Reviewed AtJanuary 19, 2024

Introduction

Infertility is when the couple fails to achieve pregnancy for one year or more after unprotected sex. It can be due to many factors, such as bacterial, viral, fungal, and parasitic infections. Other factors include genetic factors, medications, environmental toxins, systemic diseases, low sperm production, and tubal blockage. Infertility is the world's most common problem related to the male and female reproductive systems. However, infectious diseases are more responsible for infertility. In addition, infertility can impair people's economic and psychological behavior, resulting in trauma or stress. It can affect both sexes and all age groups. The calculation of male infertility is very challenging for several reasons. During the survey, the couples interviewed and the female partners who wished to have children without unprotected sex found it a difficult task. Around fifteen percent of the world's population is affected by infertility. Males are more likely to be infertile than females. Infertility is a common problem in both developed and developing countries. In developing countries, the burden of male infertility is more due to low medical resources, poor medical conditions, and the high cost of treatment.

What Is Male Infertility?

Male infertility refers to a male who cannot make a female pregnant. There may be an alteration in sperm count and motility. It may be due to less semen production and semen quality. Various infections like sexually transmitted diseases and infectious diseases can also lead to male infertility.

What Is the Global Incidence of Infertility?

Worldwide, around seventy-two million people experience fertility issues. According to the World Health Organization (WHO), around sixty to eighty million people have infertility worldwide. It varies in different countries and affects around fifteen percent of people. Moreover, infertility is increasing in several populations. About ten percent of people in the United States are infertile and unable to conceive after one year. Worldwide, the fertility rate in men has decreased by fifteen percent, and the age involved is younger than thirty years. According to the National Health Statistics, in 1982, the infertility rate increased from 4.5 million to 6.7 million, 7.26 million in 2002, and decreased to 6.71 million from 2006 to 2010.

What Is the Incidence of Infertility in India?

According to the World Health Organization (WHO), the prevalence of infertility ranges from four percent to seventeen percent. In addition, the infertility rates vary among different states of India, from four percent in Himachal Pradesh, Maharashtra, and Uttar Pradesh, five percent in Andhra Pradesh, and fifteen percent in Kashmir. Furthermore, the rate of infertility varies based on the castes and tribes in the different states of India. Male infertility is not reported as female infertility because of the cultural differences and dominance of the males.

Around forty percent of females are affected by infertility, and forty percent of males are affected. Twenty percent of both sexes are affected. According to WHO, 20 percent of males, 30 percent of females, and 25 percent were involved in both sex, and 15 percent of a single partner engaged in infertility. In India, around 50 percent of male infertility is due to reproductive disorders and anomalies.

Why Is There a Rise in Male Infertility?

The decline in sperm quality, count, and motility can lead to male infertility. However, geographically, the incidence of male infertility is more due to sperm quality than sperm count. In addition, it may be due to nutritional, environmental, and socioeconomic factors. The incidence of abnormalities of the male genital tract and testicular cancers is increasing in various countries.

The global incidence of male infertility depends on the studies done by the researchers. Globally, 12 to 15 percent of couples. Concerning male infertility, the exact prevalence of the condition is doubtful because of the not reporting condition. In 1980, there was an increase in male infertility cases due to semen quality. However, according to the survey done in 1992, there was no previous history of male infertility. Between 1940 and 1990, the male sperm count in healthy men declined by 1.2 percent per year. In 2000, a research study was done, and the results showed a decline in sperm count.

According to the France study done between 1988 to 2007, around 1.5 percent of people showed a decrease in sperm count, and 5.5 percent showed sperm motility. The sperm count declined by 52 percent between 1973 and 2018. Male infertility can range between three percent to 13 percent. 4.5 percent of people are affected in North America, 9 percent in Australia, 42.4 percent in Nigeria, 6.4 percent in Siberia, and 12 percent in Europe. Infertile males are more prone to develop testicular cancer.

Only male fertility is documented in India, and male infertility is not appropriately reported. However, the research study conducted in India showed around a thirty percent decline in sperm count and a 23 percent decrease in sperm motility and morphology. The incidence of an increase in sperm morphological abnormalities can result in impairment of spermatogenesis. According to the All India Institute of Medical Sciences (AIIMS) doctors, around 12 to 18 million/ml. These are due to the temperature exposure from the laptops, dryers, welders, and steel and cement factories. The increase in environmental heat can raise the temperature of the scrotum and cause an impact on sperm production.

A study conducted in Calcutta between 1981 to 1985 and 2000 to 2006 showed a decline in sperm motility and semen volume. Aging is an essential factor in the reduction of sperm count. Around 90 percent of seminiferous tubules contain spermatids at 20 to 30 years of age and decline to 50 percent at 40 to 50 years of age. Men aged more than eighty years comprise only ten percent of spermatids.

Conclusion:

Male infertility is the most common problem that the world faces. It can affect the psychological and physical health of couples. It can be due to many reasons, including infections, workplace heat exposure, and in-utero exposures. Male infertility is increasing more in developing countries, including India. Therefore, it needs to look for the cause of the factors that rise in the trends of male factor infertility. The issue to be researched is to decrease the prevalence of the condition. In the future, healthcare providers, including doctors, nurses, surveyors, and researchers, need to work together to reduce religious and cultural beliefs and create societal awareness.

Frequently Asked Questions

1.

Is Infertility Present in All Men with Varicocele?

Not all men with varicocele experience infertility. While varicocele, a condition characterized by swollen veins in the scrotum, can potentially impact sperm quality and production due to increased testicular temperature, it does not uniformly lead to infertility. The degree of infertility risk varies; some individuals with varicocele may maintain normal fertility, while others could face challenges in conceiving. Consulting a medical professional and undergoing fertility assessments can help determine the extent of any varicocele-related fertility issues.

2.

Does Clomid Enhance Male Fertility?

Clomid, a medication commonly used to address female infertility, can also be prescribed for men as an off-label treatment to enhance fertility potentially. By stimulating the production of certain hormones like Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), Clomid may encourage increased sperm production in men with low sperm counts or hormonal imbalances. However, its effectiveness varies from individual to individual, and medical guidance is essential to determine if Clomid is a suitable option for improving male fertility.

3.

What Leads to Male Infertility in Cystic Fibrosis?

Male infertility in cystic fibrosis is primarily attributed to the absence of the vas deferens, a tube responsible for transporting sperm from the testes to the urethra. This absence leads to obstructive azoospermia, where sperm cannot be released into the semen. Despite this challenge, assisted reproductive techniques like surgical sperm retrieval can allow men with cystic fibrosis to have biological children. These techniques involve directly collecting sperm from the testes for use in In Vitro Fertilization (IVF) procedures, enabling parenthood for individuals with this condition.

4.

Are There Natural Treatments for Male Infertility?

Certain lifestyle adjustments and supplements might have a positive impact on male fertility. Maintaining a healthy weight, managing stress, avoiding excessive alcohol and tobacco use, and ensuring a balanced diet of nutrients like zinc and antioxidants can contribute to better fertility outcomes. While these approaches may help improve sperm health and production to some extent, it is important to note that severe male infertility cases could require more advanced medical interventions for effective treatment. Consulting a healthcare professional is advisable before making significant changes.
 

5.

Does Male Infertility Tend to Be Hereditary?

Yes, male infertility can have a hereditary component. Genetic factors play a role in influencing sperm production, quality, and reproductive functions. Conditions such as chromosomal abnormalities and Y chromosome microdeletions can be inherited and impact male fertility. However, it is important to recognize that infertility is a complicated issue depending on different factors such as genetics, lifestyle, environmental factors, and overall health.

6.

What Role Does a Urologist Play in Treating Male Infertility?

A urologist is crucial in treating male infertility by providing specialized medical expertise. They conduct comprehensive assessments to identify potential causes of infertility, including hormonal imbalances, anatomical issues, or genetic factors. Urologists offer personalized treatment plans, which might involve lifestyle adjustments, medications, or surgical interventions. They also guide couples through assisted reproductive technologies like In Vitro Fertilization (IVF) or Intracytoplasmic Sperm Injection (ICSI) when necessary, aiming to address male infertility and improve the chances of successful conception.

7.

Can Hernia Surgery Lead to Male Infertility?

Hernia surgery typically does not lead to male infertility, as the surgical procedure is focused on repairing the hernia and does not directly affect the reproductive organs. However, there might be exceptions if the surgery involves complications that impact the testicles or surrounding structures. Generally, the risk of infertility due to hernia surgery is quite low. If one has concerns, discussing them with a healthcare professional before undergoing surgery can provide reassurance and clarity regarding potential effects on fertility.

8.

How Can a Man Determine If He Is Infertile?

Determining male infertility involves a medical evaluation by a urologist or fertility specialist. This assessment includes a semen analysis to examine sperm count, motility, and morphology. Hormone-level tests and physical exams might also be conducted. If conception has not occurred after a year of unprotected intercourse, seeking professional guidance is advisable. A healthcare provider can interpret test results and provide insights into potential fertility issues, helping individuals understand their fertility status and explore appropriate treatments or interventions.

9.

What Factors Can Harm Sperm Cells in Males?

Several factors can harm sperm cells in males. Elevated temperatures from frequent hot baths or wearing tight underwear, exposure to environmental toxins, excessive alcohol consumption, smoking, drug use, certain medications, and chronic stress can negatively impact sperm quality and production. Maintaining a healthy lifestyle, avoiding harmful substances, and managing stress can help mitigate these potential risks and promote better sperm health.

10.

What Contributes to the Production of Weak Sperm in Males?

Various factors can contribute to the production of weak sperm in males. These include hormonal imbalances, nutritional deficiencies, excessive heat exposure to the testicles, medical diseases, smoking, and excessive alcohol consumption. Adopting a healthy lifestyle, ensuring proper nutrition, managing stress, and avoiding harmful habits can improve sperm quality and address issues related to weak sperm production. Consulting a healthcare professional can provide further guidance and evaluation if concerns persist.
 

11.

Is There a Way to Test Sperm Count at Home?

While there are at-home sperm testing kits available, they may not provide the same accuracy as laboratory assessments. These kits typically evaluate sperm count and sometimes motility, but factors like sperm morphology and overall quality might not be thoroughly assessed. For more comprehensive and reliable results, it is recommended to undergo a professional semen analysis conducted by a medical facility. This ensures accurate diagnosis and appropriate guidance if any fertility concerns arise.
 

12.

What Is the Recommended Frequency of Ejaculation for Males?

The recommended frequency of ejaculation for males varies based on individual circumstances. Generally, there is no strict rule, but regular ejaculation (two to three times per week) can help maintain sperm quality and prevent the buildup of older, potentially less viable sperm. However, excessive ejaculation might temporarily reduce sperm count per ejaculation. Balance is key – maintaining regular sexual activity without overdoing it can contribute to better overall reproductive health.

13.

Are There Medications That Hurt Sperm Viability?

Some medications can impact sperm viability. Chemotherapy drugs, certain antibiotics, and medications that affect hormone levels might negatively affect sperm production and quality. However, the specific impact can vary among individuals. If one is concerned about medication's effect on sperm, discussing with a healthcare specialist who can provide detailed advice and alternative treatment options is essential.
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Dr. Sameer Kumar
Dr. Sameer Kumar

Obstetrics and Gynecology

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