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HomeAnswersPharmacologymao inhibitorIs it acceptable to take Levothyroxine with an MAO inhibitor?

Can Levothyroxine be taken along with MAO inhibitor?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At April 8, 2017
Reviewed AtJuly 29, 2022

Patient's Query

Hello doctor,

I am wondering if I can take Levothyroxine along with MAO inhibitor? Also, I have taken Etizolam for a sleep disorder, how long do I need to wait before I can take MAO inhibitor?

Answered by Dr. Amrit Agarwal


Welcome to icliniq.com.

You can take Levothyroxine with MAO (monoamine oxidase) inhibitor.

The list of contraindicated drugs is as follows.

  1. Amphetamines.
  2. Cocaine.
  3. MDMA (3,4-Methylenedioxymethamphetamine).
  4. Opiates.
  5. Barbiturates.
  6. Decongestants and allergy medications.
  7. Diet pills.
  8. Methylphenidate.
  9. Asthma inhalers.
  10. Meperidine.
  11. Levodopa.
  12. Dopamine.
  13. Carbamazepine.
  14. Certain antihypertensive medications.
  15. Sympathomimetic amines (direct and indirect acting) including pseudoephedrine and ephedrine.

MAO inhibitor after being stopped, show an increase of neural monoamine levels for 2 to 3 weeks.

Concomitant use of MAO inhibitor with Etizolam show side effects like sedation, dizziness, etc., but not fatal side effects are reported.

  • Also, if you want to stop the use of any drug, taper down to three-fourth of its dose for five days, then consecutively to half of its dose for seven days. Then reduce it further to one-fourth dose for ten days.
  • Meanwhile, do brisk walking or exercise daily for 20 minutes. That will cause the release of anti-stress hormone endorphins.
  • Also, indulge yourself in learning something new that will also cause the release of serotonin. Use of perfumes also leads to increase epinephrine levels, that are the hormones responsible for mood elevation and sound sleep.

For more information consult a pharmacologist online --> https://www.icliniq.com/ask-a-doctor-online/pharmacologist

Patient's Query

Thank you, doctor,

That was very helpful. How long does it take for Etizolam to leave the body completely? I used to take it regularly, but have just taken two tablets of 0.5 mg, a week ago. Is my body already cleaned off it?

Answered by Dr. Amrit Agarwal


Welcome back to icliniq.com.

  • Etizolam is a drug which has a hepatic metabolism, and its half-life is 6 to 8 hours. So, it is entirely washed out from the body within 16 to 18 hours maximum.
  • Yes, your body is cleared from Etizolam.

For further queries consult a pharmacologist online --> https://www.icliniq.com/ask-a-doctor-online/pharmacologist

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Amrit Agarwal
Dr. Amrit Agarwal


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