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Q. I got exposed to Abiraterone indirectly. Will it affect my pregnancy?

Answered by
Dr. Arul Amuthan
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 28, 2020 and last reviewed on: Dec 30, 2020

Hi doctor,

I am six weeks pregnant and I might have exposed to a drug called Abiraterone indirectly. I had a patient who takes the medication. I did not handle the medicine directly but I am wondering whether can I get exposed to the medicine indirectly from the patient room. Is it possible to have indirect exposure to this medication? Does the residue of this medication can enter the skin and cause some systemic response?

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#

Hi,

Welcome to icliniq.com.

Abiraterone is toxic. It can show toxicity when it enters our blood. When it is consumed orally, only fifty percent of it gets absorbed and the remaining gets excreted without absorption. So if the drug is exposed to the skin, eyes, and nose, the rate of absorption is not significant. This drug will not show any toxicity with a single dose. On repeated use, it produces toxicity even to the fetus too. As your exposure is up to the skin level, you need not worry. You are exposed to the patient for a single time and not multiple times, so there is nothing to worry. Considering all the above facts, I am sure you will not develop any toxic effects from Abiraterone.

Thank you doctor,

I got exposed to the patient multiple times as I was the nurse in the room. But I avoided touching things in that room without gloves except the door handle. His wife gave the medication to the patient and I do not think whether she washed the hands after doing it. The nursing assistant also cleaned the patient's feces by wearing gloves. I am worried whether any residue present on the door handle cause any toxic effect on me.

#

Hi,

Welcome back to icliniq.com.

Through the skin, the rate of absorption is not significant enough to cause systemic toxicity. You are doing the right practice. Handling the patient with gloves is necessary. The chemical (drug) is mixed with some excipients to produce a tablet. The drug is released from the tablet when the water is added to it. Once the tablet is put into the mouth, it starts releasing. But I do not think the drug is released outside the water or saliva. If the wife has handled the tablet in a dry state it will cause no issues to anybody. You are absolutely safe from it.


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